How thalidomide is effective against cerebral infarction - health is wealth

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Tuesday, 6 March 2018

How thalidomide is effective against cerebral infarction

How thalidomide is effective against cerebral infarction Scientists have studied thalidomide's target protein, cereblon (CRBN), and its binding protein, AMP-activated protein kinase (AMPK), which plays an important role in maintaining intracellular energy homeostasis in the brain. Through their study, they revealed that thalidomide inhibits the activity of AMPK via CRBN under oxidative stress and suppresses nerve cell death. http://ift.tt/eA8V8J

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